Browsing by Author "Kaya, T"
Now showing items 1-20 of 27
-
Altered contractile responsiveness in ileal longitudinal muscle after total gastrectomy in a rat model
Gokgoz, S; Koyluoglu, G; Saraydin, S; Kaya, T; Gursoy, S; Sen, M (SPRINGER-VERLAG, 2004)Purpose To test the hypothesis that the changes in ileal smooth muscle contractility accompanying postgastrectomy syndromes are agonist-specific, we investigated the effects of potassium chloride (KCl), carbachol, substance ... -
Changes in the nitric oxide system of rat myometrium during midgestation and delivery at term
Kaya, T; Cetin, A; Sarioglu, Y (ACADEMIC PRESS LTD, 1998)The aims of this study were to investigate whether a nitric oxide (NO) system is present in the pregnant rat myometrium and whether it differentially inhibits myometrial contractility during midgestation and delivery at ... -
Chloride channel blockers 5-nitro-2-(3-phenylpropylamino) benzoic acid and anthracene-9-carboxylic acid inhibit contractions of pregnant rat myometrium in vitro
OBJECTIVE: We compared in vitro relaxant effect of chloride channel modulators, such as 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB) and anthracene-9-carboxylate (9-AC), and beta (2)-adrenergic agonists, such as ... -
Comparative relaxant effects of YC-1 and DETA/NO on spontaneous contractions and the levels of cGMP of isolated pregnant rat myometrium
Demirkoprulu, N; Cetin, M; Bagcivan, I; Kaya, T; Soydan, AS; Karadas, B; Cetin, A (ELSEVIER SCIENCE BV, 2005)This study was designed to compare the effects of YCA (3-(5-hydroxymethyl-2'-furyl)-1-benzyl indazole), a nitric oxide (NO)independent soluble guanylate cyclase activator, and diethylenetriamine-NONOate (DETA/NO), a NO ... -
Comparison of effects of cyclooxygenase inhibitors on myometrial contraction and constriction of ductus arteriosus in rats
Karadas, B; Kaya, T; Bagcivan, I; Kaloglu, C; Guvenal, T; Cetin, A; Soydan, AS (ELSEVIER SCIENCE BV, 2004)The aim of this study was to compare the tocolytic effect of a selective cylooxygenase-2 inhibitor, DFU (5,5-dimethyl-3(3-fluorophenyl)4-(4-methylsulphonyl)phenyl-2(5H)-furanone), indomethacin and nimesulide on myometrial ... -
Comparison of effects of formoterol and BRL 37344 on isolated term-pregnant rat myometrial strips in vitro
Yurtcu, N; Cetin, A; Karadas, B; Imir, AG; Kaya, T; Erselcan, T; Bagcivan, I; Cetin, M (ELSEVIER SCIENCE BV, 2006)This study was designed to compare the effects of beta-adrenoccptoy agonists formoterol and BRL 37344 on spontaneous contractions and the levels of cAMP and cGMP of myometrial strips isolated from timed-pregnant rats. ... -
Comparison of the effects of nimesulide and 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanone (DFU) on contractions of isolated pregnant human myometrium
Karadas, B; Kaya, T; Guvenal, T; Cetin, M; Divrik, I; Cetin, A (ELSEVIER SCIENCE BV, 2004)Objective: To compare the effects of 5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulphonyl) phenyl-2(5H)-furanone (DFU) and nimesulide, selective COX-2 inhibitors, on the amplitude and frequency of KCI-, oxytocin-, and ... -
Effect of additional testosterone on purinergic responses in isolated rabbit corpus cavernosum strips
Kaya, T; Sarioglu, Y; Goksu, OC; Yildirim, S; Yildirim, K (ACADEMIC PRESS LTD, 1998)Recently, it has been demonstrated that the endothelium of corpus cavernosum (CC) plays an important role on smooth muscle relaxation, which is crucial to initiate and maintain erection. We investigated the effect of ... -
Effect of deferoxamine and sympathectomy on vasospasm following subarachnoid hemorrhage
We examined the effects of subarachnoid hemorrhage (SAH) and treatment with deferoxamine (DFO) or sympathectomy on vascular smooth muscle function, as well as the underlying mechanisms involved, by recording the responses ... -
Effect of endothelin-1 on spontaneous contractions and effects of nimodipine and isradipine on endothelin-1-induced contractions in myometrial strips isolated from normal pregnant and preeclamptic women
Kaya, T; Cetin, A; Cetin, M; Sarioglu, Y (MUNKSGAARD INT PUBL LTD, 1998)Background. To examine the effect of endothelin-l (ET-1) on spontaneous contractile activity and the effects of nimodipine and isradipine on ET-l-induced contractile responses in myometrial strips isolated from normal ... -
Effect of L-NAME on decreased ileal muscle contractility induced by peritonitis in rats
Koyluoglu, G; Kaya, T; Bagcivan, I; Yildiz, T (W B SAUNDERS CO, 2002)Background/Purpose: It is now well established that intestinal inflammation is associated with disturbed contractility. The aim of this study was to determine the effects of peritonitis on longitudinal ileum smooth muscle ... -
Effect of magnesium sulfate, isradipine, and ritodrine on contractions of myometrium: pregnant human and rat
Background. Magnesium sulfate, isradipine, and ritodrine are smooth muscle relaxants used for treating preterm labor. The aim of this study is to investigate the action profile of these drugs on the amplitude and frequency ... -
Effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid, anthracene-9-carboxylate, and zaprinast on endothelin-1-induced contractions of pregnant rat myometrium
Kaya, T; Guvenal, T; Karadas, B; Cetin, A; Soydan, AS (ELSEVIER SCI IRELAND LTD, 2002)Objective: The effects of 5-nitro-2-(3-phenylpropylamino) benzoic acid (NPPB), anthracene-9-carboxylate (9-AC) (chloride channel blockers) and zaprinast (an inhibitor of phosphodiesterase-5) on endothelin-1 (ET-1) induced ... -
Effects of ceftriaxone sodium on in vitro gallbladder contractility in guinea pigs
Arpacik, M; Ceran, C; Kaya, T; Karadas, B; Sarac, B; Koyluoglu, G (ACADEMIC PRESS INC ELSEVIER SCIENCE, 2004)Background/Purpose. It has been reported that ceftriaxone may induce the formation of gallstones. Changes of gallbladder motility may play a role in this phenomenon. The present study was designed to analyze the gallbladder ... -
Effects of endothelin-1 and calcium channel blockers on contractions in human myometrium - A study on myometrial strips from normal and diabetic pregnant women
Kaya, T; Cetin, A; Cetin, M; Sarioglu, Y (SCI PRINTERS & PUBL INC, 1999)OBJECTIVE: We studied the effect of endothelin (ET)-1 on spontaneous contractions and the effects of nimodipine and isradipine on ET-l-induced contractions in myometrial tissue from normal and diabetic pregnant women. STUDY ... -
Effects of intravenous anesthetic agents on pregnant myometrium
Emergent or elective surgical procedures under general anesthesia may be required during pregnancy for some patients. For this reason, effects of anesthetics on uterine contractions are important. General anesthesia is not ... -
Effects of nimodipine and isradipine on endothelin-1-induced contraction of pregnant rat myometrium
Kaya, T; Cetin, A; Cetin, M; Sarioglu, Y (ELSEVIER SCIENCE BV, 1998)The purpose of this study was to investigate the effect of nimodipine and isradipine on endothelin-1-induced contractions of isolated pregnant rat myometrium. Endothelin-1 at 10(-10)-10(-8) M dose-dependently increased the ... -
Effects of sympathectomy on endothelin-1 and histamine responses of rabbit carotid artery
Utkan, T; Kaya, T; Sarioglu, Y (ELSEVIER SCIENCE INC, 1997)1. The effects of chronic sympathectomy on contractile responses of rabbit common carotid artery was studied in vitro. 2. Endothelin-1 (ET-I), histamine, KCl and papaverine concentration-response curves of sympathectomized ... -
In vitro effects of intravenous anesthetics on the sphincter of Oddi strips of sheep
Background: Intravenous anesthetics are often used for conscious sedation in endoscopic retrograde cholangiopancreatography (ERCP) and endoscopic sphincter of Oddi (SO) manometry. This study was designed to investigate the ... -
Inhibitor effect of omeprazole in isolated human myometrial smooth muscle
Yildirim, K; Sarioglu, Y; Kaya, T; Cetin, A; Yildirim, S (PERGAMON-ELSEVIER SCIENCE LTD, 2001)The aim of the present study was to investigate the effect of omeprazole, an H+-K+-ATPase inhibitor, in myometrial smooth muscle strips from women undergoing elective caesarean section at term. Isolated myometrial strips ...